rus eng
Issues / 05/15 Print

Hepatoprotector Dironax influence on growth and development of geese

UDC 619:612.015:636.598

Gubaidullin A.S., Skovorodin E.N., Strunin B.p., Kilmetova I.R.

Summary. Liver is involved in many biochemical processes in the body, keeping it in a certain balance. Reducing the barrier function of the liver is accompanied by accumulation in the blood and tissues of harmful substances causing degeneration and necrosis of organs. Many medicines have undesirable side effects and are ineffective. Hepatoprotectors are used as special medicines to increase resistance of the liver against various pathological factors, enhance its antitoxic function, stimulate activity of enzyme systems and contribute to its functioning under various damages. Hepatoprotector Dironax synthesized in LTD. Basis (Ufa) is proposed for the treatment of hepatitis of unproductive small domestic animals. Aim of the work is to set the influence of Dironax on the growth and development of geese and liver. Authors studied preventive efficacy of Dironax on productive animals. Studies were carried out on goslings of white Hungarian breed in age from 1 to 6 months. Dironax in a dose of 5 mg/kg of body weight was included in addition to the diet of the experimental group of poultry. Preparation was given in the form of feeding, starting from the 1st month to the 6th month old. Authors found positive influence of preparation on growth intensity of body weight of goslings. Relative increase in the test group was 71% higher than the control to 6%. More intensive growth of liver was noted in the experimental group of goslings. Thus, use of Dironax as a feed additive actively promotes growth and development of liver during the first month of use, which leads to an intense increase in body weight geese hereinafter.

Keywords: ducklings, Hungarian white breed, liver, hepatitis, diet, feed additive, hepatoprotector, Dironax, live weight gain.

References:

1. Belousov Iu.B., Kukes V.G., Lepakhin V.K., Petrov V.I. Klinicheskaia farmakologiia: natsionalnoe rukovodstvo [Clinical pharmacology: national guidance]. – GEOTAR-Media. – Moscow, 2009. – 976 p.

2. Donald K. Farmakologicheskie preparaty v veterinarnoi meditsine [Pharmacological preparations in veterinary medicine]. – Akvarium. – Moscow, 2002. – p. 445.

3. Dudarev A.A., Kilmetova I.R., Strunin B.P. Primenenie gepatoprotektora Dironaksa dlia lecheniia domashnikh zhivotnykh [Use of hepatoprotector Dironax for treatment of domestic animals]. – Ufa, 2014. – 26 p.

4. Krasniuk I.I., G.V. Mikhailova, Zamarenov N.A. Farmatsevticheskaia gomeopatiia [Pharmaceutical homeopathy]. – Akademiia. – Moscow, 2005. – 272 p.

5. Manto I.E. Sostav aminokislot plazmy krovi pri gepatobiliarnoi patologii [Composition of amino acids in blood plasma of hepatobiliary pathologies]. – Ukraina. – Kiev, 1996. – 238 p.

6. Markova I.V., Mikhailov I.B., Nezhentsev M.V. Farmakologiia [Pharmacology]. – Foliant. – Saint-Petersburg, 2001 – 415 p.

7. Nugumanova G.N., Tagasheva R.G., Bukharov S.V., Mukmenova N.A., Oludina Iu.N., Sattarova L.F., Strunin B.P., Antipov V.A., Gurevich P.A. Biologicheskaia aktivnost proizvodnykh izatina, funktsionalizirovannogo prostranstvenno zatrudnennymi fenolami [Biological activity of isatin derivatives functionalized by hindered phenols]. – Vestnik Kazanskogo tekhnologicheskogo universiteta. – Kazan, 2010 (10). – pp. 91-95.

8. Okovityi S.V., Bezborodkina N.N., Uleichik S.G., Solianik A.V., Shulenin S.N. Gepatoprotektory [Hepatoprotectors]. – GEOTAR. – Moscow, 2010. – 112 p.

9. Phaneendra, B., Hepatoprotective herbs: an overwiev / B. Phaneedra // IJPRD. Vol 3(3), 2011. – P.105 – 111.

10. Williams, J.M. The liver and biliary tract / J.M. Williams, D.N. Jacqui. – BSAVA Manual of Canine and Feline Abdominan Surgery, BSAVA, 2005. – P. 168-194.

Author affiliation:

Gubaidullin Ainur S., post-graduate student of the department of morphology, pathology, pharmacy and non-contagious diseases of the Bashkir State Agrarian University; 34, 50 Let Oktiabria st., Ufa, 450001; e-mail: jagnur@mail.ru.

Skovorodin Evgenii N., D.Sc. in Veterinary Medicine, professor of the department of morphology, pathology, pharmacy and non-contagious diseases of the Bashkir State Agrarian University; 34, 50 Let Oktiabria st., Ufa, 450001; e-mail: skovorodinen@mail.ru.

Strunin Boris P., D.Sc. in Technics, director of LTD. Basis; 112/1, Industrialnoe shosse st., Ufa, 450027; phone: 8(347)242-74-56; e-mail: polyvitt@yandex.ru.

Responsible for the correspondence with the editorial board: Kilmetova Inna R., D.Sc. in Veterinary Medicine, vice director for veterinary medicine of LTD. Polyvit; 112/1, Industrialnoe shosse st., Ufa, 450027; phone: 8(347)242-74-56; e-mail: innakilmetova@yandex.ru.

 

2011 © Veterinaria Kubani by Internet-Image