Natural resistance indicators in pigs using microbiological fermentation of feed for the prevention of mycotoxicosis caused by T-2 toxin and aflatoxin B1

УДК 619; 576; 579.62
DOI 10.33861/2071-8020-2025-6-12-14

Original Empirical Research

Mironova O.A., Mironova A.A., Vasilenko V.N., Mironova L.P.

Abstract. It was found that in three-month-old piglets fed from the age of one month with compound feed containing T-2 toxin and aflatoxin in amounts of 0.1-0.2 mg/kg: 1) the blood levels of total protein, albumin, FANK, BASK, LASK, B-lymphocytes, NK-lymphocytes were significantly lower, and ESR was significantly higher compared to the control group; 2) leukopenia develops with a 35.5% decrease in the total leukocyte count compared to control animals. A shift in the leukogram occurs toward a decrease in the relative content of band and segmented neutrophils; an increase in the percentage of eosinophils; a decrease in the percentage of lymphocytes; 3) in three-month-old piglets fed fermented feed containing T-2 toxin and aflatoxin in amounts of 0.1 - 0.2 mg/kg before fermentation, the total leukocyte count, leukogram structure, levels of total protein, albumin, globulin, the number of T-lymphocytes, B-lymphocytes, NK lymphocytes, FANK, BASK, LASK, and ESR were close to the control.

Keywords: mycotoxins, biofermentation, cellular and humoral immunity, leukocyte formula, pigs.

Author affiliation:

Vasilenko Vyacheslav N., D.Sc. in Agriculture, Corresponding Member of the Russian Academy of Sciences; Senior Scientific Researcher of the Federal Rostov Agricultural Research Center; 0, Rostov hghw., Novocherkassk, Rostov region, 346421.

Mironova Olga A., Ph. D. in Biology, Head of the basic department of biology and ecosystem security of the Institute of ecology of the Peoples’ Friendship University of Russia named after Patrice Lumumba; All-Russian Plant Quarantine Centre; 6, Miklukho-Maklaya st., Moscow, 117198.

Mironova Lyudmila P., D. Sc. in Veterinary Medicine, professor of the department of therapy and propaedeutics of the Don State Agrarian University; Chief Scientific Researcher of the Federal Rostov Agricultural Research Center;24, Krivoshlykova st., Persianovsky sttl., Oktyabrsky district, Rostov region, 346493; e-mail: mironova_lp@mail.ru.

Responsible for correspondence with the editorial board: Mironova Anna A., D.Sc. in Veterinary Medicine, senior scientific researcher of the Federal Rostov Agricultural Research Center; 0, Rostov hghw., Novocherkassk, Rostov region, 346421; phone: 8-903-4718275; e-mail: aa_mironova@mail.ru.

Authors’ Contribution: the manuscript was written with the input of all authors. All authors approved the final version of the manuscript.

Conflict of Interest Statement: the authors declare no conflict of interest.