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УДК 619:616.98:578.835.2:636.22/.28:616-071 DOI 10.33861/2071-8020-2023-6-3-7 Krivonos R. A., Chernykh O. Yu., Shevchenko A. A., Mishchenko A. V., Mishchenko V. A., Chernov A. N. Summary. An analysis of materials from numerous cases of research on diseases of the large horned cattle manifested by vesicular lesions is presented in the article. Vesicles, ulcers and erosions appear on the mucous membranes of the oral and nasal cavities, gums, nasal skin, tongue, and nasal tract, which can be found in the large horned cattle at many diseases of contagious etiology, such as: foot-and-mouth disease, vesicular stomatitis, viral diarrhea, infectious rhinotracheitis, papular stomatitis, malignant catarrhal fever, and non-contagious etiology: in case of poisoning with ulcerative-erosive lesions of the oral cavity, tongue, poisonous plants and chemicals, toxicosis. The authors provided data on clinical signs, pathological findings and laboratory tests for a number of the most common infectious diseases with similar symptoms. It has been established that diagnosis must be carried out comprehensively, taking into account epizootological indices, symptoms of manifestation, pathomorphological changes and always confirming with the results of laboratory tests, since it is the isolation of the causative agent of the disease that will make it possible to make a final diagnosis. Keywords: foot-and-mouth disease, epizootics, vesicular stomatitis, viral diarrhea, infectious rhinotracheitis, papular stomatitis, malignant catarrhal fever, toxicosis, poisoning, vesicles, ulcers, erosions. Author affiliation: Krivonos Roman A., Ph.D. in Veterinary Medicine, docent of the department of parasitology, veterinary-sanitary expertise and animal hygiene of the Kuban State Agrarian University named after I. T. Trubilin; 13, Kalinina st., Krasnodar, 350044; e-mail: uv@krasnodar.ru. Shevchenko Aleksandr A., D. Sc. in Veterinary Medicine, professor, head of the department of microbiology, epizootology and virology of the Kuban State Agrarian University named after I. T. Trubilin; 13, Kalinina st., Krasnodar, 350044; phone: 8-918-1549461; e-mail: shevshenkoalexsandr@yandex.ru. Mishchenko Aleksey V., Ph.D. in Veterinary Medicine, senior scientific researcher of the information analysis center of the Federal Centre of Animal Health; mcrd. Yurjevets, Vladimir, Russia, 600901; phone: 8-4922-261551; e-mail: a.mischenko@mcx.ru. Mishchenko Vladimir A., D.Sc. in Veterinary Medicine, professor, chief scientific researcher of the Laboratory of the prevention of diseases of pigs and horned cattle of the Federal Centre of Animal Health; mcrd. Yurjevets, Vladimir, Russia, 600901; phone: 8-4922-261551; e-mail: mishenko@arriah.ru. Chernov Albert N., D.Sc. in Biology, docent, deputy director for research of the Krasnodar Scientific Center for Animal Husbandry and Veterinary Medicine; 1, 1 Liniya st., Krasnodar, 350004; phone: 8-927-4036300; e-mail: rt-kazan@mail.ru. Responsible for correspondence with the editorial board: Chernykh Oleg Yu., D.Sc. in Veterinary Medicine, docent, professor 17 of the Department of microbiology, epizootology and virology of the Kuban State Agrarian University named after I.T. Trubilin; 13, Kalinina st., Krasnodar, 350044; phone: 8-918-4956659; e-mail: gukkvl50@kubanvet.ru.
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