Immunohaematological indices of growing pigs

UDC 619:161.15:57.083.3:636.[4:083.35]:470.51/.54

Isaeva A.G., Krivonogova A.S.

Summary. Immune and haematological studies were conducted on clinically healthy pigs from one to six months of age in farms, unfavorable for infectious diseases. No abnormalities in the cardiovascular, respiratory, digestive systems in experimental animals were revealed. Average live weight of animals matched for age. It was found that maximum content of red blood cells, hemoglobin and hematocrit is observed in animals at the age of 5-6 months in the region of the Middle Urals. High number of white blood cells was observed in animals of all ages. Maximum number of leukocytes was found in pigs of 3-4 months of age, which is to 34.6% more than in animals of 1-2 months of age and to 65% more than the upper limit of the regional standards – 7,0-16,0 th/mcl. Low levels of T- and B-index in animals of all age groups at the minimum in animals of 1-2 months of age – 0,83 ± 0,07 may indicate deficiency of cellular immunity, as an index of T- and B-lymphocytes at physiologically normal functioning of the immune system is determined to be 1.5-2 u. High rates of T- and B-cell lymphocyte populations and circulating immune complexes in 3-4-month animals indicate a high degree of activation of nonspecific protection of the organism in this age. Authors suggested that it is necessary to conduct researches of regulatory indicators, taking into account the technology of feeding and territorial peculiarities of the region.

Key words: pigs, immune system, hematological indices, T- and B-lymphocyte population, T/B index, leucocyte T-index, circulating immune complexes, leucocytes, erythrocytes.

References:

1. Baksheev A.N. Stanovlenie, porodnye osobennosti i vozmozhnosti korrektsii immunnoi sistemy u svinei [Formation, breed features and correction capabilities of immune system in pigs]. – Novosibirsk, 1998. – 32 p.

2. Donnik I.M., Bolshakov V.N. Ekologicheskie aspekty agropromyshlennogo proizvodstva Uralskogo regiona [Environmental aspects of agricultural production of Ural region]. – Yekaterinburg, 2010. – pp. 52-60.

3. Donnik I.M., Shkuratova I.A., Khasina E.I., Yakubenko E.V. Dinamika nakopleniia ekotoksikantov v biologicheskikh resursakh regionov s intensivnoi antropogennoi nagruzkoi [Accumulation dynamics of ecotoxicants in biological resources in the region of intense anthropogenic impact]. – Veterinariia Kubani. – Krasnodar, 2012 (6). – pp. 21-24.

4. Karaulov A.V. Klinicheskaia immunologiia [Clinical immunology]. – MIA. – Moscow, 1999. – 604 p.

5. Loginov S.I., Smirnov P.I., Trunov A.I. Immunnye kompleksy u zhivotnykh i cheloveka: norma i patologiia [Immune complexes in animals and humans: norm and pathology]. – Novosibirsk, 1999. – 144 p.

6. Simonian G.A., Khisamutdinov F.F. Veterinarnaia gematologiia [Veterinary haemotology]. – Kolos. – Moscow, 1995. – 256 p.

7. Smirnov P.N., Efanova N.V., Khramtsov V.V. Panel naibolee informativnykh testov dlia otsenki rezistentnosti zhivotnykh [Panel of the most informative tests to evaluate resistance of animals]. – Novosibirsk, 2007. – 40 p.

8. Talanov G.A., Smirnov A.M. Antropogennye poliutanty, ikh veterinarnosanitarnoe i toksikologicheskoe znachenie [Anthropogenic pollutants: veterinary and sanitary and toxicological significance]. – Moscow, 1994. – pp. 34-42.

9. Trufakin V.A., Trunova L.A. Immunologicheskie pokazateli formirovaniia ekologicheski obuslovlennoi patologii [Immunological parameters of formation of environmentally induced pathology]. – Vestnik RAMN. – Moscow, 1994 (17). – pp. 15-18.

10. Frimel G. Immunologicheskie metody [Immunological methods]. – Meditsina. – Moscow, 1987. – 472 p.

11. Shakhov A.G., Argunov M.N., Sereda S.V. Zagriaznenie okruzhaiushchei sredy – vazhneishii faktor ukhudsheniia produktivnogo zdorovia zhivotnykh [Environmental pollution – a key factor in the deterioration of productive animal health]. – Medok. – Kazan, 2006. – pp. 139-142.

12. Shkuratova I.A. Korrektsiia immunnogo statusa u vysokoproduktivnykh korov [Correction of immune status of highly productive cows]. – Veterinariia. – Moscow, 2008 (2). – pp. 11-12.

13. Shkuratova I.A., Donnik I.M., Vereshchak N.A. Kharakteristika pokazatelei immunnoi sistemy i metody korrektsii immunnoi nedostatochnosti u zhivotnykh Uralskogo regiona [Characteristics of immune system and methods of correction of immune deficiency in animals in Ural region]. – Yekaterinburg, 2012. – 127 p.

14. Shkuratova I.A., Donnik I.M., Isaeva A.G., Krivonogova A.S. Ekologobiologicheskie osobennosti krupnogo rogatogo skota v usloviiakh tekhnogeneza [Ecological and biological features of large horned cattle in conditions of technogenesis]. – 2015: 366-369.

15. Chereshnev V.A., Yushkov B.G., Klimin V.G., Lebedeva E.V. Immunofiziologiia [Immune fisiology]. – UrO RAN. – Yekaterinburg, 2002. – 269 p.

Author affiliation:

Krivonogova Anna S., Ph.D. in Biology, docent of the department of infectious and non-infectious pathology of the Ural State Agrarian University; 42, Karla Libknekhta st., Yekaterinburg, 620075; phone: 8 (343)371-33-63; e-mail: academy@ursaca.ru.

Responsible for correspondence with the editorial board: Isaeva Albina G., Ph.D. in Biology, senior scientific researcher of the Ural Scientific Research Veterinary Institute; 112 a, Belinskogo st., Yekaterinburg, 620219; phone: 8(343)2572044; e-mail: isaeva.05@bk.ru.