Medicinal approaches to increase resistance of cows to heat stress in conditions of Krasnodar region

УДК 619:615.4 / 636.2.034
DOI 10.33861/2071-8020-2025-4-14-16

Original Empirical Research

Kuzminova E. V., Semenenko M. P., Zheleznyakova K. A., Goncharova D. I.

Summary. The article presents research materials on the development of medicinal approaches to increasing the resistance of cows to heat stress in Krasnodar region. The aim of the study was to investigate the efficiency of Revinorm in treating heat stroke in cows. Monitoring of microclimatic parameters carried out on the territory of the dairy farm and calculated parameters of the temperature-humidity index established that heat stress in cows of varying degrees of severity was recorded on all days of the study. At the same time, several episodes of extreme heat were recorded, when cases of heat stroke were diagnosed among dairy cattle. During heat wave periods, two groups of cows with clinical manifestations of heat stroke (10 heads in each group) were formed using the paired analogue method. For the medicinal treatment of heat stroke, all cows were initially given a lytic mixture intramuscularly, after which the experimental group was given Revinorm, and the control group was given the treatment protocol adopted on the farm. It has been established that the inclusion of the drug revinorm in the regimen for stopping heat stroke in cows significantly increases the efficacy of therapeutic measures. Laboratory studies have shown that during heat stroke in cows, markers of endogenous intoxication increase in the blood, in particular the toxic fraction of medium-weight molecules. After 5 days of heat stroke treatment, a decrease in MSM 254 levels was recorded in cows, with the best results in the group receiving revinorm. Based on the obtained results, Revinorm can be effectively used for intensive therapy and emergency care for heat stroke in the large horned cattle.

Keywords: cows, heat stress, heat stroke, therapy, Revinorm, blood, endogenous intoxication, medium-weight molecules.

Author affiliation:

Semenenko Marina P., Dr. Sc. in Veterinary Medicine, docent, Head of the Department of Pharmacology of the Krasnodar Research Centre for Animal Husbandry and Veterinary Medicine; 1, 1-ya Liniya st., Krasnodar, 350004; phone: 8-918-4612663; е-mail: sever291@mail.ru.

Zheleznyakova Ksenia A., Ph.D. in Economics, Senior Scientific Researcher of the Department of Pharmacology of the Krasnodar Research Centre for Animal Husbandry and Veterinary Medicine; 1, 1-ya Liniya st., Krasnodar, 350004; phone: 8-918-4442242; е-mail: ksenia.andreevna0708@gmail.ru.

Goncharova Darya I., student of the Kuban State Medical University of the Ministry of Health of the Russian Federation; 4, Mitrofan Sedin st., Krasnodar, 350063; phone: 8-918-3529120; e-mail: daria021102@mail.ru.

Responsible for correspondence with the editors: Kuzminova Elena V., D.Sc. in Veterinary Medicine, Associate Professor, Chief Scientific Researcher of the Department of Pharmacology of the Krasnodar Research Centre for Animal Husbandry and Veterinary Medicine; 1, 1-ya Liniya st., Krasnodar, 350004; phone: 8-918-4198369; е-mail: niva1430@mail.ru.

Author’s Contribution:

Kuzminova E. V.: conceptualization, data curation, methodology, project administration, resources, supervision, writing - review & editing.

Semenenko M. P.: conceptualization, data curation, methodology, project administration, resources, supervision, writing - review & editing.

Zheleznyakova K. A.: formal analysis, investigation, validation, visualization, writing - original draft preparation.

Goncharova D. I.: investigation, validation, visualization.

Conflict of Interest Statement: the authors declare no conflict of interest.