Eimeriostatics efficacy in combination with probiotic at eimeriosis in broiler chickens

УДК 619.614:636.5:621.
DOI 10.33861/2071-8020-2024-4-29-30

Makhieva B. M., Aliev A. Yu., Polunochkina T. V.

Summary. Eimerioses are widespread in Dagestan and occupy a leading position among bird diseases of parasitic etiology registered in the region. Epizootics of chicken eimeriosis cause great economic damage to poultry farms due to the massive mortality of chickens and are a serious parasitic enemy for poultry farming, taking advantage of the slightest shortcomings and violations of veterinary and sanitary rules for keeping, feeding, caring for and breeding birds. Epizootic safety of poultry farms mainly depends on the health status of the poultry population. According to the veterinary reports of the Veterinary Committee of the Republic of Dagestan, the death of chickens from eimeriosis is expressed annually in tens of thousands of birds and accounts for over 80% of the number of dead birds in the group of infectious and invasive diseases. Eimeria are quickly capable of developing resistance to anticoccidial drugs, therefore, during therapy, it is necessary to periodically rotate anticoccidial drugs, as well as practical experimental work with new drugs in order to increase the effectiveness of veterinary measures. In a production experiment for the treatment of eimeriosis in broiler chickens, the following drugs were taken: Amprolium 25% and Toltrex 2.5%. Suspension for oral use, produced by VIC. Animal Health, contains the active ingredient toltrazuril - 50 mg, as well as auxiliary components up to 1 ml. The drug has a wide spectrum of anticoccidial action and is effective against Eimeria mitis, Eimeria acervulina, Eimeria tenella and other species of Eimeria parasitizing broiler chickens. The finely dispersed molecule of the active substance and the uniform distribution of toltrazuril in the suspension ensure high bioavailability and prolongation of the drug in the body of the bird. Toltrazuril is excreted from the body, mainly unchanged (70%), as well as in the form of metabolites in feces and partially in urine. Toltrex 2.5% in terms of the degree of impact on the body according to GOST 12.1.007, belongs to hazard class 3 (moderately hazardous substances). The comparative effectiveness of the drugs Toltrex 2.5% and Amprolium 25% for eimeriosis of birds was determined. Studies have shown that Toltrex 2.5%, at a dose of 1 ml of the drug per 1 liter of drinking water, turned out to be more effective in the treatment of eimeriosis in broiler chickens.

Keywords: industrial poultry farming, broiler chickens, eimeriosis, invasion, Toltrex, Amprolium, efficiency, oocyst, poultry manure.

Author affiliation:

Aliev Ayub Yu., D. Sc. in Veterinary Medicine, Director of the Caspian Zonal Scientific Research Veterinary Institute; 88, Dakhadaeva st., Makhachkala, Republic of Dagestan, 367000; e-mail: alievayb1@mail.ru.

Polunochkina Tatyana V., VIC Group Leading Veterinary Consultant for Poultry Farming; building 681, block 30137, Ostrovtsy vlg., Ramenskoe city district, Moscow region, Russia, 140125; e-mail: polunochkina@vicgroup.ru.

Responsible for correspondence with the editorial board: Makhieva Bakhu M., Ph. D. in Veterinary Medicine, Leading Scientific Researcher of the Laboratory for the study of invasive diseases of agricultural animals and poultry of the Caspian Zonal Scientific Research Veterinary Institute - branch of the Federal Agrarian Scientific Center of the Republic of Dagestan; 88, Dakhadaeva st., Makhachkala, Republic of Dagestan, 367000; e-mail: bahumahieva66@gmail.com.