УДК 619:615.285 DOI 10.33861/2071-8020-2022-4-27-29 Levchenko M.A. Summary. New chemical preparations are being developed to overcome the rapidly developing resistance in houseflies (Musca domestica L.) to the insecticides used against them. The use of a combination of active substances from different chemical classes in the form of a bait makes it possible to slow down the development of resistance and increase the efficacy of measures against this type of insect. The research was carried out in the laboratory of the All-Russian Scientific Research Institute of Veterinary Entomology and Arachnology - branch of the Tyumen Scientific Center of the Siberian Branch of the Russian Academy of Sciences and under the production conditions of the poultry farm of Pyshminskaya LTD. Adult houseflies Musca domestica L. - females and males of 3-5 days of age of the laboratory population without segregation by sex, - were used for this purpose. In the laboratory, the effective rational doses of the above insecticides were determined by the methods of group feeding, feeding and the method of evaluating food insecticidal baits in the fight against flies from 0.000002 to 4% concentrations. According to the results of laboratory studies, it was found that the optimal doses that cause 100% death of insects were 0.002% for ivermectin and 0.02% for chlorfenapyr. The insecticidal effectiveness of the developed Mukhnet IC bait against flies under production conditions on the first day after treatment of the livestock building was 94%. The high insecticidal effect of the carried-out measures lasted 6 days. The restoration of the number of insects to the previous level occurred on the 10th day. The patent of the Russian Federation was obtained for this method of using ivermectin and chlorfenapyr. Keywords: ivermectin, chlorfenapyr, effective optimal doses, bait, housefly, Musca domestica, production testing, veterinary significance, fly population control. References: 1. Ibragimkhalilova I.V., Eremina O.Yu. Razrabotka metoda otsenki otravlennykh primanok i sravneniye kontaktnogo i kishechnogo deystviya insektitsidov na primere komnatnoy mukhi Musca domestica L. [Development of a method for evaluating poisoned baits and comparison of the contact and intestinal effects of insecticides on the example of the housefly Musca domestica L.]. - 2007 (12). - pp. 56-62. 2. Kostina M.N. Osnovnye napravleniya sovershenstvovaniya dezinsek-tsionnykh meropriyatiy na sovremennom etape [Main directions of improving disinsection measures at the present stage]. - Dezdelo. - 2003 (1). - 51 p. 3. Metodicheskie ukazaniya 3.5.2.1759-3 ‘Metody opredeleniya effektivnosti insektitsidov, akaritsidov, regulyatorov razvitiya i repellentov, ispolzuemykh v meditsinskoy dezinsektsii [Methodological guidelines of 3.5.2.1759-3 ‘Methods for determining the effectiveness of insecticides, acaricides, development regulators and repellents used in medical disinsection’]. - 2003. 4. Primenenie insektitsidnoy kombinatsii primanochnogo sredstva protiv komnatnykh mukh [Use of an insecticidal bait combination against houseflies]. -Patent of the Russian Federation. - 2739502. 5. Sokolyanskaya M.P., Amirkhanov D.V. Puti preodoleniya rezistentnosti nasekomykh k insektitsidam [Ways of overcoming insect resistance to insecticides]. - Bulletin of the Bashkir State Agrarian University. - Ufa, 2006 (2). -pp. 7-12. 6. Sokolyanskaya M.P., Amirkhanov D.V. Esteraznye mekhanizmy formirovaniya rezistentnosti u komnatnoy mukhi (Musca domestica) k insektitsidam raznykh khimicheskikh klassov [Esterase mechanisms of resistance formation in houseflies (Musca domestica) to insecticides of different chemical classes]. -Agrokhimiya. - 2008 (7). - pp. 56-61. 7. Khimicheskie metody borby s perenoschikami i parazitami, imeyushchimi znachenie dlya zdravookhraneniya VOZ [Chemical methods of control of vectors and parasites that are important for public health WHO]. - 2000: 140 p. 8-11. Vide supra. Author affiliation: Levchenko Mikhail A., Ph.D. in Veterinary Medicine, Head of the Laboratory of veterinary problems in animal husbandry of the All-Russian Scientific Research Institute of Veterinary Entomology and Arachnology; 2, Institutskaya st., Tyumen, 625041; phone: 8-3452-258558; e-mail: levchenko-m-a@mail.ru - responsible for correspondence with the editorial board.
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