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Turchenko A.N, Petenko A.I., Koba I.S., Gorpinchenko E.A., Novikova E.N., Reshetka M.B. Summary Presently in Krasnodar region a course is taken on large dairy farms and dairy complexes of closed type. This technology creates a severe discomfort for productive animals, resulting in a high morbidity of breeding stock, especially in the early postpartum period. Treatment of endometritis and mastitis in cows leads to the contamination of milk and meat with preparations: antibiotics, hormones and others, that cause toxicoses, allergic reactions and disbacterioses in humans. Most acceptable alternative to the use of currently widely applicable in the veterinary gynecology antimicrobial agents is the use of probiotics, as the most environmentally natural rivals of pathogenic and conditionally pathogenic agents, causing endometritis and mastitis in cows. Probiotics prevent acute postpartum endometritis in 50-60% of treated animals. Multiplicity of treatments of probiotic-treated cows is at the level of positive control and was 1,7-2,2 times, respectively, while the number of days of infertility was also at the level of control and was 85,7-98,2 day. Application of probiotics Monosporin and Prolam for the prevention of obstetric and gynecological pathology is the perspective direction requiring further research to identify optimum period of drug administration after parturition, well as their doses and multiplicity. Key words: probiotics, Monosporin, Prolam, endometritis, obstetrics, gynecology, parturition, prophylaxis of endometritis. References - Varganov A.I., Vidyakin A.S. Opyt primeneniya Biosana pri lechenii endometritov u korov [Experience of application of Biosan in the treatment of endometritis in cows]. – 1987.
- Varganov A.I., Opekunov K.A. Vliyanie biologicheskogo preparata Biosan pri skrytykh endometritax u korov [Influence of biological preparation Biosan at latent endometritis in cows]. – Kirovsk, 1981.
- Ventskovsky B.M., Tovstanovskaya V.A. Primenenie probiotikov v kompleksnoy terapii i profilaktike vospalitelnykh zabolevaniy v akusherstve i ginekologii [Use of probiotics in complex therapy of inflammatory diseases in obsterics and gynecology]. // – Krasnodar, 2009.
- Ilinsky E.V. О nekotorykh posledstviyakh lekarstvennoy terapii, ispolzuemoy v akushersko-ginekologicheskoy praktike [On some implications of medication used in obstetric and gynecological practice]. – Riga, 1997: pp. 68-70.
- Kleyko E.I. Effektivnost primeneniya Batsella v ratsionakh korov [Efficiency of application of Bacell in the rations of cows]. – Effektivnoe zhivotnovodstvo, 2009. – # 8.
- Nazarov M.V., Shevkoplyas V.N., Gavrilov B.V., Tuzov A.I. Fitopreparat Mastotsid dlya lecheniya i profilaktiki mastita u korov [Phytopreparation Mastoсid for treatment and prophylaxis of mastitis in cows]. – Krasnodar, 2001.
- Gandhi A.B. Probiotics in veterinary use / Gandhi A.B. Nagarathnam Т.// Poultry Guide, 1990; Т. 27. N 3. - р. 43-49.
- Denev S. Probiotics - past, present and future / Denev S. // Bulg.J.agr.Sc., 1996; Vol.2,N 4. - P. 445-474.
Author affiliation Petenko Aleksander I., D.Sc. in Agricultural Sciences, professor, head of the department of physiology and feeding of agricultural animals of the Kuban State Agrarian University; 13, Kalinina st., Krasnodar, 350044; ph.: 8(918) 44-16-472. Koba Igor S., D.Sc. in Veterinary Medicine, senior scientific researcher of the laboratory of obstetrics and gynecology of agricultural animals of the Krasnodar Scientific-Research Veterinary Institute; 1, 1st Line, Krasnodar, 350004; ph.:8 (918) 44-16- 472; e-mail: knivi@list.ru. Gorpinchenko Evgeny A., Ph. D. in Veterinary Medicine, docent of the department of therapy and pharmacology of the Kuban State Agrarian University; 13, Kalinina st., Krasnodar, 350044; ph.: 8(918) 48-59-409; e-mail: kubeag@mail.ru. Novikova Elena N., scientific researcher of the Krasnodar Scientific-Research Veterinary Institute; 1, 1st Line, Krasnodar, 350004; ph.: 8(928) 04-30-748; e-mail: knivi@list.ru. Reshetka Mikhail B., scientific researcher of the Krasnodar Scientific-Research Veterinary Institute; 1, 1st Line, Krasnodar, 350004; ph.: 8(906)43-32-775; e-mail: knivi@list.ru. Responsible for correspondence with the editorial board: Turchenko Aleksey N., D.Sc. in Veterinary Medicine, professor, head of the laboratory of obstetrics and gynecology of agricultural animals of the Krasnodar Scientific-Research Veterinary Institute; 1, 1st Line, Krasnodar, 350004; ph.: 8 (918)19- 75-462; e-mail: knivi@list.ru.
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