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DOI 10.33861/2071-8020-2020-2-24-26 Sevostyanova O.I., Orobets V.A., Sokolova E.A., Kastarnova E.S. Summary. Heat stress is still one of the main problemsin poultry breeding. Depression of the general condition, decreased productivity, worsened conversion parameters, decreased egg production are just some of the adverse effects of stress factors. As one of the ways to deal with heat stress, veterinary pharmacology creates different constructions of mono- and multivitamin complexes. These complexes are designed to reduce or completely neutralize the negative effects of stress. Despite the declared by the manufacturers balance of feed for poultry, the need for additional introduction of vitamin complexes into the diet is confirmed by hundreds of scientific studies and world practices. This article has the results of the study evaluating the impact of the developed aggregate-resistant vitamin-mineral complex based on selenium with a particle size of 20 to 60 nm on broiler chickens by Cobb-500 cross raised under heat stress. Like an analogue drug, was used Solvimin Selenium. It was found that anemia was recorded on the 21st day. The observed leukocytosis is an increase in the number of neutrophils and basophils in the peripheral blood. The biochemical composition of the blood of broiler chickens shows a pronounced stress effect on the body of birds of all experimental groups. All experimental groups had a decrease in total protein, albumin and urea with an increase in creatinine after 7 days from the start of the study. Changing the level of glucose in the blood serum allows us to conclude, that broilers in the control group have more stress tolerance. There are deviations not only in the control group, but also in the experimental groups. But, birds treated with vitamin-mineral complexes have the development of adaptive mechanisms, and a less pronounced negative effect of the temperature stress factor is noted. Keywords: vitamin-mineral complexes, poultry farming, broiler chickens, stress, selenium, vitamins, biochemistry, hematology, adaptation, organic farming. Author affiliation: Orobets Vladimir A., D.Sc. in Veterinary Medicine, professor, head of the department of therapy and pharmacology of the Stavropol State Agrarian University; 12, Zootehnichesky Lane, Stavropol, 355017. Sokolova Ekaterina A., Ph.D. in Biology, lecturer of the educational-methodical department of the faculty of secondary vocational education of the Stavropol State Agrarian University; 12, Zootehnichesky Lane, Stavropol, 355017. Kastarnova Elena S., post-graduate student of the department of therapy and pharmacology of the Stavropol State Agrarian University; 12, Zootehnichesky Lane, Stavropol, 355017. Responsible for correspondence with the editorial board: Sevostyanova Olga I., Ph.D. in Biology, docent of the department of therapy and pharmacology of the Stavropol State Agrarian University; 12, Zootehnichesky Lane, Stavropol, 355017; phone:8-918-7717334;e-mail: sevostyanova19@mail.ru.
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