Liver pathology problem in high yielding cows

UDC 619:616.36

LIVER PATHOLOGY PROBLEM IN HIGH YIELDING COWS

Mishchenko V.A., Mishchenko A.V., Chernykh O.Yu.

Summary. High yielding cows with intensive metabolism are sensitive even to minor violations of feeding, conditions of detention and react to it more pronounced metabolic disorders affecting their immunobiological status. Most critically significant period of time, which determines the health and productivity of cows during lactation, the so-called perinatal period, which includes 3 weeks before calving and 2-3 weeks after calving. Three weeks before calving is a short but important period in the life of a cow, which affects the health and productivity in the subsequent lactation, as well as the safety of the whole herd. With the approach of calving concentration of estrogen in the blood remains high or even increases. Data on epizootological researches, clinical examination of animals, pathological changes and laboratory studies identified liver dystrophy in calved high yielding cows caused by metabolic disorders accompanied by a postpartum and "nutritional" stress. Biochemical blood tests indicates that 60-90% of calved cows were lack of sugars, zinc, copper, manganese, magnesium, carotene, gammaglobulins. Enzyme activity transamination characterizing functional state of the liver and other organs: AST, ALT, alkaline phosphatase and lactate dehydrogenase is increased in the blood plasma of 50-80% highly productive cows. These changes indicate a significant functional disturbances of parenchymal organs.

Keywords: high-yielding cows, metabolism, fatty liver dystrophy, diet, acidosis, ketosis, trace element deficiency, degenerative changes, feeding, content.

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Author affiliation:

Mishchenko Aleksey V., Ph.D. in Veterinary Medicine, senior researcher of the laboratory of diagnostics of farm animals’ diseases of the Federal State Establishment "Federal Centre of Animal Health" (FSE "All-Russian Research Institute of Animal Health"); mcrd. Yurjevets, Vladimir, 600901; phone: (4922) 26-17-65; e-mail: mishenko@arriah.ru.

Mishchenko Vladimir A., D.Sc. in Veterinary Medicine, professor, chief expert for bovine diseases of Federal State Establishment "Federal Centre of Animal Health" (FSE "All-Russian Research Institute of Animal Health"); mcrd. Yurjevets, Vladimir, 600901; phone: (4922) 26-17-65 20-83; e-mail: mishenko@arriah.ru.

Responsible for correspondence with the editorial board: Chernykh Oleg Yu., D.Sc. in Veterinary Medicine, director of the Kropotkin territorial veterinary laboratory; 303, Krasnoarmeyskaya st., Kropotkin, 352380; phone: 8(86138) 6-23-14; e-mail: gukkvl50@kubanvet.ru.