Clinical diagnostics’ errors at foot-and-mouth disease in large horned cattle

UDC 619:616.98:578.835.2:636.22/ .28:616-071

CLINICAL DIAGNOSTICS’ ERRORS AT FOOT-AND-MOUTH DISEASE IN LARGE HORNED CATTLE

Mishchenko A.V., Mishchenko V.A., Dzhailidi G.A., Krivonos R.A., Chernykh O.Yu.

Summary. Foot-and-mouth disease is a highly contagious disease of cloven-hoofed animals. It is a worldwide problem that arrests attention of veterinary services from many countries and international organizations. Results of epidemiological survey and clinical examination data are grounds for placing restrictions and carrying out laboratory tests for foot-and-mouth disease. Diagnostics of foot-and-mouth disease is the first and very important step in the system of infection control. Most expeditious methods of diagnostics foot and mouth disease epizootic survey data are farms clinical survey of animals and postmortem examinations that reveal massive vesicular lesions in susceptible animals. Article demonstrates analysis of registered false-positive and false-negative clinical diagnoses for foot and mouth disease in cattle in the territory of the Soviet Union (1975-1991) and the Russian Federation (1992-2013). Analysis of results of epizootological examination of foot-and-mouth disease foci and clinical survey of animals testified that often veterinarians considered that pathology was caused by poisoning with poisonous plants, various chemicals (including alkalis and salts) or other suspected infectious diseases (pasteurellosis, bovine smallpox). It was shown that 66.7% out of 102 false-positive clinical diagnoses were presented by ulcerous and erosive lesions on tongues (noninfectious etiology), 20.6% – by malignant catarrhal fever and 11.8% – by bovine pseudopox. In case of 25 false-negative clinical diagnoses (with subsequent foot and mouth disease confirmation) 75% were supposedly presented by poisoning.

Key words: foot-and-mouth disease, large horned cattle, clinical diagnostics, differential diagnostics, false-positive diagnosis, false-negative diagnosis, ulcerous and erosive lesions on tongue, malignant catarrhal fever, infectious rhinotracheitis, bovine pseudopox, poisoning.

References

1. Talman G., Nekler A., Felfe P. Epizootiya yashchura 1982 v Rostoke, Neybrandenburge i predlozheniya dlya budushchey strategii borby s yashchurom v Germanii [Epizooty of foot-and-mouth disease in 1982 in Rostock, Neybrandenburg and suggestions for future strategy against foot-and-mouth disease in Germany]. – Vladimir, 1992. – pp. 31-40.

2. Vydrin V.N., Shevtsov I.A., Mishchenko V.A. Erozionno-yazvennye porazheniya v rotovoy polosti krupnogo rogatogo skota [Erosive and ulcerative lesions in the oral cavity of large horned cattle]. – Veterinariya. – Moscow, 2002 (8). – pp. 9-10.

3. Mishchenko A.V., Mishchenko V.A., Borisov V.V. Patologichesky protsess pri eksperimentalnom i spontannom yashchure krupnogo rogatogo skota [Pathological process at experimental and spontaneous bovine foot-and-mouth disease]. – Veterinariya. – Moscow, 2010 (4). – pp. 25-27.

4. Mishchenko A.V., Mishchenko V.A., Dudnikov S.A. Opyt likvidatsii yashchura v pervichnykh ochagakh [Experience of liquidation of foot-and-mouth primary outbreaks]. – Veterinariya. – Moscow, 2011 (11). – pp. 7-12.

5. Mikhalishin D.V. Prodolzhitelnost immuniteta u vaktsinirovannogo protivoyashchurnoy emulsionnoy vaktsinoy krupnogo rogatogo skota v zavisimosti ot ee aktivnosti [Immunity duration in vaccinated against foot-and-mouth disease emulsion vaccine cattle depending on its activity]. – Vetkorm. – Moscow, 2013 (5). – pp. 29-30.

6. Foot-and-mouth disease//OIE Terrestrial Manual 2012, Chapter 2.1.5., 145-173

7. Geering A., Lubroth J. Preparation of foot-and-mouth disease contingency plans// Paris, 2011, 94 p.

Author affiliation:

Mishchenko Aleksey V., Ph.D. in Veterinary Medicine, senior researcher of the laboratory of diagnostics of farm animals’ diseases of the Federal State Establishment "Federal Centre of Animal Health" (FSE "All-Russian Research Institute of Animal Health"); mcrd. Yurjevets, Vladimir, Russia, 600901; phone: (4922) 26-17-65; e-mail: mishenko@arriah.ru.

Mishchenko Vladimir A., D.Sc. in Veterinary Medicine, professor, chief expert for bovine diseases of Federal State Establishment "Federal Centre of Animal Health" (FSE "All-Russian Research Institute of Animal Health"); mcrd. Yurjevets, Vladimir, Russia, 600901; phone: (4922) 26-17-65 20-83; e-mail: mishenko@arriah.ru.

Dzhailidi Georgy A., Ph. D. in Biology, Head of the State Veterinary Department of Krasnodar region; 36, Rashpilevskaya st., Krasnodar, 350000; phone: 8 (861) 262-19-23; e-mail: dga@uv.krasnodar.ru.

Krivonos Roman A., Deputy Head of the State Veterinary Department of Krasnodar region; 36, Rashpilevskaya st., Krasnodar, 350000; phone: 8(861)262-19-23; e-mail: epiz@uv.krasnodar.ru.

Responsible for correspondence with the editorial board: Chernykh Oleg Yu., D.Sc. in Veterinary Medicine, director of the Kropotkin territorial veterinary laboratory; 303, Krasnoarmeyskaya st., Kropotkin, 352380; phone: 8(86138) 6-23-14; e-mail: gukkvl50@kubanvet.ru.