Correction of immune status and increase of efficiency of bovine leucosis’ diagnostics

Dmitriev A.F., Novoseltsev G.G., Chernykh O.Yu.

Summary

The aim of our work is the evaluation of efficiency of roncoleukin use for immune status correction and increase of reability in diagnostics of young bovine leucose. Bovine leucose virus has immunosuppresive properties, what can develop different pathology and the possibility of intrauterine infection of offsprings is not excluded. Herewith, it is important to do early and accurate diagnosis of heifers. Correction of the young bovine’s immune system can increase the realibility of serological diagnosis. The heifers (57 heads) born from the cows with different level of predisposition to the leucosis have been tested. The cow’s immune correction by the roncoleukin didn’t influence on the increase of the efficiency of immune diagnostics of young bovine leucose.

Key words: diagnosis, virus of bovine leucose, cattle, infection, immunotolerance, immunodeficiency, roncoleukin, serology, immune system, monitoring.

References

1. Smirnov P.N., Khramtsov V.V., Smirnova V.V., Razumovskaya V.V. Diagnostika leykoza krupnogo rogatogo skota: Metodicheskie rekomendatsii [Diagnostics of bovine leucose: Methodic recommendations]. – Novosibirsk. – 2000. – 21 p. Print. (in Russ.).
2. Gulyukin M.I. Sistema monitoringa leykoza krupnogo rogatogo skota v Rossiyskoy Federatsii [Monitoring system of bovine leucose in the Russian Federation]. – Veterinarny consultant (2007): pp. 5-18. – Print. (in Russ.).
3. Krikun V. A. Leykoz krupnogo rogatogo skota i immunologicheskaya tolerantnost [Leucose of large horned cattle and immunological tolerance]. – Veterinariya (2003): pp. 7-9. – Print. (in Russ.).
4. Apalkin V.A., Gulyukin M.I., Petrov N.I. Leykoz krupnogo rogatogo skota (diagnostika i ozdorovitelnye meropriyatiya): Rekomendatsii [Leucose of large horned cattle (diagnostics, recreational measures)]. – Saint-Petersburg – 2005. – 87 p. – Print. (in Russ.).
5. Amirokov M.A., Khramtsov V.V., Mager S.N. Osnovnye polozheniya kompleksnoy sistemy ozdorovleniya i profilaktiki leykoza krupnogo rogatogo skota na s/kh predpriyatiyakh Novosibirskoy oblasti [Basic positions of an integrated system of rehabilitation and treatment of bovine leucose in enterprises of Novosibirsk Region]. – Veterinarny vrach (2007): pp. 5-6. – Print. (in Russ.).
6. Zinnapov F.F. Molekulyarnaya genodiagnostika leykoza krupnogo rogatogo skota [Molecular gene diagnostics of bovine leucose]. – Kazan. – 2008. – 25 p. – Print. (in Russ.).
7. Kovalyuk N.V., Satsuk V.F., Machulskaya E.V. Sovremennye metody diagnostiki leykoza krupnogo rogatogo skota [Modern methods of diagnostics of bovine leucose]. – Veterinariya Kubani (2007). – Print. (in Russ.).
8. Galeev R.F., Khusainov R.F., Chernov A.N. Vnutriutrobnoe infitsirovanie embrionov virusom leykoza krupnogo rogatogo skota [Intrauterine infection of embryos by virus of bovine leucose]. – Veterinarny Vrach (2008): pp. 24-26. – Print. (in Russ.).
9. Razumovskaya V.V. Sovershenstvovanie sistemy upravleniya epizooticheskim processom leykoza i brutsellyoza krupnogo rogatogo skota [Improvement of management system of epizootic process of leucose and brucellose in cattle]. – Barnaul. – 2004. – 39 p. – Print. (in Russ.).

Author affiliation

Dmitriev Anatoly F., D.Sc. in Biology, professor of the Stavropol State Agrarian University; phone: 8(962)0187475; e-mail: anatolidmitriev@yandex.ru.

Chernykh Oleg Yu., D.Sc. in Veterinary Medicine, director of the Kropotkin regional veterinary laboratory; 303, Krasnoarmeyskaya st., Kropotkin, 352380; phone: 8(918)4956659; e-mail: gukkl50@kubanvet.ru.

Responsible for correspondence with the editorial board: Novoseltsev Georgy G., honored veterinarian of the Kuban, chief of the veterinary service of Gulkevichsky district; 6, Severnaya st., Gulkevichi, 352190; phone: 8(918)4448381; e-mail: gyargyar1@gmail.com.