ÓÄÊ619:615.33:616.2-08]:636.2
DOI 10.33861/2071-8020-2025-6-7-8
Original Empirical Research
Koba I. S., Khakhov L. A., Kozlov Yu. V.
Abstract. Modern livestock farming requires effective solutions for controlling bacterial respiratory infections, such as mycoplasmosis caused by Mycoplasma bovis. High treatment costs have driven the development of new antimicrobial drugs. The article presents the results of a comparative study on the effectiveness of the Russian Tulatrin and the imported Draxxin in the treatment of respiratory mycoplasmosis in calves. The experiment involved 30 calves divided into three groups of 10 animals each. Diagnosis included clinical examination, PCR, ELISA, and pathological examination. Both drugs led to 100% elimination of M. bovis and the absence of secondary bacterial microflora. In the control group, disease progression was observed with the development of severe complications (pneumonia, neurological disorders, keratitis) and a mortality rate of 35%. The Russian preparation Tulatrin demonstrated comparable microbiological but higher clinical efficacy compared to Draxxin, ensuring faster symptom relief and better recovery of the animals. Its use, especially for early prevention in at-risk groups (newborns, before transportation), is economically feasible and allows for the creation of effective protection during critical periods.
Keywords: large horned cattle, calves, mycoplasmosis, Mycoplasma bovis, tulathromycin, Tulatrin, Draxxin, respiratory diseases, comparative efficacy, therapy.
Author affiliation:
Koba Igor S., D. Sc. in Veterinary Medicine, Professor, Head of the Department of Epizootology, Microbiology and Veterinary-Sanitary Expertise of the Moscow State Academy of Veterinary Medicine and Biotechnology – MVA named after K. I. Skryabin; 23, Akademika Skryabina st., Moscow, 109472; e-mail: vetdoctor@mail.ru.
Khakhov Latif A., Ph. D. in Veterinary Medicine, Professor, Head of the Department of Therapy and Pharmacology of the Kuban State Agrarian University named after I. T. Trubilin; 13, Kalinina st., Krasnodar, 350044; e-mail: latif.khakhov@gmail.com.
Responsible for the correspondence with the editorial board: Kozlov Yuri V., Ph. D. in Veterinary Medicine, docent of the Department of Therapy and Pharmacology of the Kuban State Agrarian University named after I. T. Trubilin; 13, Kalinina st., Krasnodar, 350044; e-mail: yvk78@mail.ru.
Authors’ Contribution: the manuscript was written with the input of all authors. All authors approved the final version of the manuscript.
Conflict of Interest Statement: the authors declare no conflict of interest.
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