ÓÄÊ 619:615.285
DOI 10.33861/2071-8020-2024-6-46-48
Levchenko M. A.
Summary. The need to use safe and effective insecticides increases every year. Such agents include, among other things, active substances of plant origin, which have high biological effectiveness against harmful arthropods. Thymol (2-isopropyl-5-methylphenol) is an important phenolic monoterpene obtained from the essential oil of some members of the Laminaceae family. When compared with plant compounds, it exhibits high activity, and when compared with synthetic substances, it may be significantly less toxic against target insects. Therefore, the purpose of this work was to evaluate some methods for increasing the activity of pesticides using thymol against harmful arthropods of veterinary, medical and agricultural importance. For this purpose, a literary analysis of the Pubmed and Elibrary databases for 2001-2024 was carried out, the search words included ‘monoterpenes’, ‘thymol’, ‘insecticide’, ‘acaricide’, ‘pesticide’, ‘toxicity’, ‘activity’, ‘modification’, ‘synthesis’, ‘synergy’. The material of the articles was taken into account if the work was performed with a separate or isolated substance thymol. As a result of the work, it was revealed that to increase the effectiveness of pesticides using thymol and their stability in the environment, the main techniques are: the method of targeted transformation of the thymol molecule and its combination with other active substances of natural and synthetic origin. In the first case, results were published showing that the toxicity of this substance against harmful arthropods increased by more than 15 times; in the second, in certain combinations with other compounds it enhanced their effect: cypermethrin by more than 4 times, deltamethrin by 3 times. Also, with various combinations with active substances of plant origin, the synergism of their mixture was ensured.
Keywords: thymol, monoterpenes, pesticides, acaricides, insecticides, toxicity, activity, modification, synthesis, synergism.
Author affiliation: Levchenko Mikhail Alekseevich, Ph. D. in Veterinary Medicine, Head of the Laboratory of Veterinary Problems in Animal Husbandry of the All-Russian Scientific Research Institute of Veterinary Entomology and Arachnology - Branch of the Federal Research Centre of the Tyumen Scientific Centre of Siberian Branch of the Russian Academy of Sciences; 2, Institutskaya st., Tyumen, 625041; phone: 8-3452-258558; e-mail: levchenko-m-a@mail.ru - responsible for correspondence with the editorial board.
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