ÓÄÊ:579.8:57.08
DOI 10.33861/2071-8020-2024-5-6-8
Pimenov N.V. Ivannikova R.F., Mohammed Z.C. Fatakhov K. F.
Summary. Literature data note the incidence of Moraxella ovis detection in infectious keratoconjunctivitis of large (less frequently) and small (more frequently) ruminants. However, the authors’ opinions regarding the pathogenicity and nosological role of this microorganism differ. In this regard, the aim of the present study was to screen for Moraxella infection in a flock of sheep under high-altitude grazing conditions and to investigate the nosological role of this microorganism. The material of the study consisted of clinical samples from sheep eyes, as well as conjunctival swabs from healthy animals. The work utilized methods of bacteriological research, mass spectrometry, disk diffusion for determining the sensitivity of microorganisms to antibiotics, and a biotest on rabbits. Out of 5 samples (three from sheep, two from goats), 3 isolates of Moraxella ovis were obtained. In three cases, the presence of M. ovis was recorded without the associative presence of potential pathogens. The virulence factors of Moraxella ovis isolates, including antibiotic resistance, have been studied. Two epizootic strains have been established, and the infection has been modeled in a rabbit biotest. Discussion and conclusion. Factors indicating the pathogenicity of M. ovis have been identified: hemolytic activity, oxidase positivity, multiple antibiotic resistance, invasiveness, and the reproducibility of the infectious-inflammatory process in a biphase test on rabbits. The obtained data indicate the etiological role of Moraxella ovis in infectious keratoconjunctivitis in small ruminants.
Keywords: Moraxella ovis, infectious keratoconjunctivitis, small cattle, nosological role, antibiotic resistance.
Author affiliation:
Ivannikova Regina F., D. Sc. in Biology, docent of the Department of Immunology and Biotechnology of the Moscow State Academy of Veterinary Medicine and Biotechnology - MVA named after K. I. Skryabin; 23, Akademika Skryabina st., Moscow, 109472; phone: 8-925-0263058; e-mail: regiotf@yandex.ru.
Mohammed Zahraa Sahib, postgraduate student of the Department of Immunology and Biotechnology of the Moscow State Academy of Veterinary Medicine and Biotechnology - MVA named after K. I. Skryabin; 23, Akademika Skryabina st., Moscow, 109472; phone: +9647710565277; e-mail: zahraasahib92@gmail.com.
Fatakhov Kurban F., Ph. D. in Veterinary Medicine, senior lecturer of the Department of Immunology and Biotechnology of the Moscow State Academy of Veterinary Medicine and Biotechnology - MVA named after K. I. Skryabin; 23, Akademika Skryabina st., Moscow, 109472; phone: 8-985-0988624; e-mail: fat.kurban1995@mail.ru.
Responsible for correspondence with the editorial board: Pimenov Nikolay V., D. Sc. in Biology, professor, Head of the Department of Immunology and Biotechnology of the Moscow State Academy of Veterinary Medicine and Biotechnology - MVA named after K. I. Skryabin; 23, Akademika Skryabina st., Moscow, 109472; phone: 8-909-9448012; e-mail: pimenov-nikolai@yandex.ru.
http://vetkuban.com/en/num5_202402.html