Pharmacological correction of metabolism in cows to reduce the risk of developing pathology of the birth and postpartum periods

DOI 10.33861/2071-8020-2021-5-10-12

Malkova N.N., Ostyakova M.E., Irkhina V.K., Shcherbinina S.A.

Summary. During pregnancy, the body of cows is very sensitive to unfavorable environmental factors, for example, errors in feeding and maintenance, which negatively affects their health, manifested by metabolic disorders, the development of pathology of the birth and postpartum periods. For the research, Holstein cows were selected two months before calving and were divided into two groups: control and experimental. Blood samples were taken from all cows, followed by a study of the biochemical composition on the first and 14 days of the experimental period, and the presence or absence of pathology of the birth process and the postpartum period was also taken into account. The results of the research have shown that impaired mineral and protein metabolism in cows in the last trimester of pregnancy is an unfavorable factor contributing to the development of retained placenta, endometritis and mastitis. The applied scheme of prophylaxis in experimental animals promoted activation of the liver and protein metabolism, as well as a decrease in the incidence of endometritis and mastitis in the postpartum period.

Keywords: cow, holstein breed, blood, biochemical studies, retention of placenta, mastitis, endometritis, selenium, tissue preparation, prevention.

References:

1.Romnenskiy R.V., Khokhlov A.V., Romnenskaya N.V. et al. Gepatopatiya stelnykh korov i ikh vliyanie na sostoyanie reproduktivnoy funktsii [Hepatopathy of pregnant cows and their influence on the state of reproductive function]. – Modern problems of science and education. – 2013 (3). – pp. 1-9.

2. Ivanova I.E., Volynkina M.G. Biokhimicheskiy status krovi vysokoproduktivnykh sukhostoynykh korov v usloviyakh OAO «PZ «Uchkhoz GAU Severnoe Zauralye» [Biochemical status of the blood of highly productive dry cows in the conditions of JSC «PZ «Uchkhoz GAU Northern Trans-Urals»]. – Bulletin of the Orenburg Agrarian University. – Orenburg, 2017 (5 (67)). – pp. 173-176.

3. Kirillov A.A., Yushmanov P.N., Batrakov A.Ya. Lechenie i profilaktika zabolevaniy pecheni u korov [Treatment and prevention of liver diseases in cows]. – Issues of legal regulation in veterinary medicine. – Saint-Petersburg, 2015 (1). – pp. 91-95.

4. Pavlenko O.B., Mironova L.P., Suleymanov S.M. et al. Kliniko-morfologicheskie izmeneniya pri subklinicheskom mastite i ego odnovremennom techenii s poslerodovym endometritom u korov [Clinical and morphological changes in subclinical mastitis and its simultaneous course with postpartum endometritis in cows]. – Veterinarnaya patologiya. – Rostov-on-Don, 2014 (2). – pp. 21-26.

5. Lozovaya E.G. Metabolicheskie aspekty embriopatiy u korov [Metabolic aspects of embryopathies in cows]. – Bulletin of the Voronezh State Agrarian University. – Voronezh, 2016 (4 (51)). – pp. 69-73.

6. Meyer D., Harvey D. Veterinarnaya laboratornaya diagnostika. Interpretatsiya i diagnostika [Veterinary laboratory diagnostics. Interpretation and Diagnostics]. – Sofion. – Moscow, 2007. – 456 p.

7. Menkova A.A., Tarasenko V.N., Andreev A.I. Azotnyy obmen i molochnaya produktivnost korov pri ispolzovanii belkovo-energeticheskogo kontsentrata v ratsionakh [Nitrogen exchange and milk productivity of cows when using protein-energy concentrate in rations]. – Bulletin of the Ulyanovsk State Agricultural Academy. – 2015 (2 (30)). – pp. 110-116.

8. Milaeva I.V., Voronin O.A., Zaitsev S.Yu. Osobennosti obmena veshchestv u laktiruyushchikh korov [Features of the metabolism of lactating cows]. – Russian Journal of Agricultural and Socio-Economic Sciences. – Orel, 2017 (2 (62)). – pp. 275-281.

9. Ryadchikov V.G. Pochemu gibnut vysokoproduktivnye korovy i kak eto ostanovit [Why highly productive cows are dying and how to stop it]. – Zemlya i zhizn. – Krasnodar, 2009 (10). – p. 8.

10. Senchenko O.V. Morfologicheskie i biokhimicheskie pokazateli krovi pervotelok cherno-pestroy porody pri vvedenii v ratsion energeticheskoy dobavki Promelakt [Morphological and biochemical parameters of the blood of first-calf heifers of the Black-and-White breed with the introduction of the energy supplement Promelakt into the diet]. – Bulletin of the Orenburg State Agrarian University. – Orenburg, 2016 (2 (58)). – pp. 116-119.

11. Blokhin A.A., Isaev V.V., Khrisanova T.D. et al. Sostoyanie immunobiokhimicheskogo gomeostaza u zdorovykh laktiruyushchikh korov i bolnykh klinicheskim mastitom [The state of immunobiochemical homeostasis in healthy lactating cows and patients with clinical mastitis]. – Issues of legal regulation in veterinary medicine. – Saint-Petersburg, 2014 (2). – pp. 118-120.

12. Avdeenko V.S., Tresnitsky S.N., Kalyuzhny I.I. et al. Subklinicheskiy ketoz kak faktor razvitiya gestoza beremennykh u korov i ego rol v vozniknovenii fetoplatsentarnoy nedostatochnosti [Subclinical ketosis as a factor in the development of gestosis of pregnant women in cows and its role in the occurrence of fetoplacental insufficiency]. – Agricultural scientific journal. – Saratov, 2017 (4). – pp. 3-7.

13. Khvostova O.V. Biokhimicheskie pokazateli krovi pri razlichnykh funktsionalnykh sostoyaniyakh pecheni krupnogo rogatogo skota [Biochemical parameters of blood in various functional states of the liver in the large horned cattle]. – Bulletin of VSMU. – Vitebsk, 2004 (3 (3)). – pp. 23-28.

14. Shilov A.M., Melnik M.V., Osiya A.O. et al. Rol defitsita magniya v patogeneze metabolicheskogo sindroma [The role of magnesium deficiency in the pathogenesis of metabolic syndrome]. – Russian medical journal. – Moscow, 2008 (21). – p. 1439.

15. Yashin I.V., Kosorlukova Z.Ya., Zotkin G.V. et al. Pokazateli belkovogo obmena u korov s endometritom posle zaderzhaniya platsenty [Indices of protein metabolism in cows with endometritis after retention of the placenta]. – Bulletin of KrasGAU. – Krasnoyarsk, 2016 (9). – pp. 200-206.

16. Vide supra.

Author affiliation:

Ostyakova Marina E., D.Sc. in Biology, Associate Professor, Director of the Far Eastern Zonal Scientific Research Veterinary Institute; 112, Severnaya st., Blagoveshchensk, Amur region, 675005; phone: 8-4162-491187; e-mail: dalznivi-innovacia@mail.ru.

Irkhina Vera K., scientific researcher of the Far Eastern Zonal Scientific Research Veterinary Institute; 112, Severnaya st., Blagoveshchensk, Amur region, 675005; phone: 8-4162-491187; e-mail: dalznivi-innovacia@mail.ru.

Shcherbinina Svetlana A., junior scientific researcher of the Far Eastern Zonal Scientific Research Veterinary Institute; 112, Severnaya st., Blagoveshchensk, Amur region, 675005; phone: 8-4162-491187; e-mail: dalznivi-innovacia@mail.ru.

Responsible for correspondence with the editorial board: Malkova Nadezhda N., Ph.D. in Biology, leading scientific researcher of the Far Eastern Zonal Scientific Research Veterinary Institute; 112, Severnaya st., Blagoveshchensk, Amur region, 675005; phone: 8-4162-491187; e-mail: dalznivi-innovacia@mail.ru.


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