Shemelkovą G.O., Verkhovskaya A.E., Soboleva G.L.,
Shemelkov E.V., Ivanov E.V., Nepoklonova I.V., Aliper T.I.
Summary. According to the monitoring of serum samples presence of specific antibodies to bovine adenovirus was revealed in 24% of samples, suggesting widespread of adenovirus infection. For the prevention of major respiratory and enteric diseases of calves seven-component combined vaccine including bovine adenovirus type 1 has been developed. Vaccine has been successfully tested in cattle farms with major infectious diseases of calves.
Key words: adenovirus, viral infections, cattle, adjuvants, vaccine, antigene activity, efficiency, prevention.
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Author affiliation:
Shemelkova Galina O., biotechnologist of the department of quality control of the Vetbiochem LLC; 16, Gamaleya st., Moscow, 123098; phone: +7 (495) 193-54-93; e-mail: shemelckova@yandex.ru.
Verkhovskaya Anna E., Ph.D. in Veterinary Medicine, deputy chief of the department of quality control of the Vetbiochem LLC; 16, Gamaleya st., Moscow, 123098; phone: +7 (495) 193-54-93; e-mail: averkchovskay@mail.ru.
Soboleva Galina L., D.Sc. in Biology, head of the department of quality control of the Vetbiochem LLC; 16, Gamaleya st., Moscow, 123098; phone: +7 (495) 193-54-93; e-mail: gsoboleva@rosvet.ru.
Ivanov Evgeny V., Ph.D. in Biology, leading scientific researcher of the Diagnostic and Prevention Research Institute for Human and Animal Diseases; 16, Gamaleya st., Moscow, 123098; phone: +7 (499) 190-75-61; e-mail: doctor2112@yandex.ru.
Nepoklonova Irina V., Ph.D. in Veterinary Medicine, manager of the department of diagnostics and prevention of virus diseases of the Diagnostic and Prevention Research Institute for Human and Animal Diseases; 16, Gamaleya st., Moscow, 123098; phone: +7 (499) 190-75-61; e-mail: info@dpri.ru.
Aliper Taras I., D.Sc. in Biology, professor, director of the NARVAC Ltd; head of the department of applied virology and biotechnology of Ivanovsky Research Institute of Virology; 16, Gamaleya str., Moscow, 123098; phone: +7 (499) 190-30-54; e-mail: aliper@narvac.com.
Responsible for correspondence with the editorial board: Shemelkov Evgeny V., Ph.D. in Veterinary Medicine, leading scientific researcher of the Diagnostic and Prevention Research Institute for Human and Animal Diseases (DPRI); 16, Gamaleya st., Moscow, 123098; phone: +7 (499) 190-75-61; e-mail: shemelkov@mail.ru.
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