Pathogenic properties of rabies virus epizootic isolates circulating in Krasnodar region

DOI 10.33861/2071-8020-2021-1-17-18

Bobrov V.A., Zabashta S.N., Chernykh O.Yu., Krivonos R.A., Chernov A.N.

Summary. An analysis of the pathogenic properties of epizootic isolates of the rabies virus circulating in Krasnodar region that must be taken into consideration developing and conducting complex of antiepizootic measures is presented in the article. The special attention is paid to pathogenicity of the studied isolates for laboratory animals. This article also addresses the problem of some isolated rabies virus isolates from disadvantaged areas of Krasnodar region that have pronounced precipitating properties. As a research task the authors attempted to assess the difference between epizootic strains of the rabies virus in terms of the degree of pathogenicity for laboratory animals. The authors conclude that both highly and slightly pathogenic rabies virus isolates circulate in Krasnodar region. This article addresses the problem of the specificity of clinical manifestations of rabies in animals in Krasnodar region. The authors analyze the results of the index of invasiveness and life expectancy of studied animals after the infection in the brain with rabies virus isolates circulating in Krasnodar region. The article summarizes some other results of the study that establish the difference between epizootic strains of rabies virus by the degree of pathogenicity for laboratory animals. As the result the article substantiates the idea of antigenic relationship of epizootic rabies virus isolates circulating around the studied territory.

Keywords: pathogenic properties of epizootic isolates, rabies virus, antiepizootic measures, specificity of clinical manifestations, rabies epizootology, Krasnodar region, laboratory animals, disadvantaged areas, invasion index.

References:

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Author affiliation:

Zabashta Sergey N., D.Sc. in Veterinary Medicine, professor of the Kuban State Agrarian University named after I.T. Trubilin; 13, Kalinina st., Krasnodar, 350044.

Chernykh Oleg Yu., D.Sc. in Veterinary Medicine, professor of the Kuban State Agrarian University named after I.T. Trubilin; 13, Kalinina st., Krasnodar, 350044; phone: 8-918-4956659; e-mail: gukkvl50@kubanvet.ru.

Krivonos Roman A., Ph.D. in Veterinary Medicine, head of the Veterinary Department of Krasnodar region; 36, Rashpilevskaya st., Krasnodar, 350000; phone: 8-861-2622869; e-mail: uv@krasnodar.ru.

Chernov Albert N., D.Sc. in Biology, Krasnodar Regional Institute of Agribusiness; 78, Machugi st., Krasnodar, 350061.

Responsible for correspondence with the editorial board: Bobrov Vadim A., postgraduate student of the Kuban State Agrarian University named after I.T. Trubilin; 13, Kalinina st., Krasnodar, 350044; phone: 8-918-4911900; e-mail: bobrov_vadim@rambler.ru.


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